Safely Buy Votrient ( Pazopanib Hcl ) from Canada Prescriptions Plus.

Indications

Votrient is a cancer medication used to treat advanced kidney cancer (renal cell carcinoma) and soft tissue sarcoma (a type of tumour).

Pazopanib is a kinase inhibitor that prevents the growth and spread of cancerous cells in your body by affecting receptors in your vascular system and elsewhere. Thanks to these inhibitory actions, Votrient helps treat advanced kidney cancer and prevents soft tissue sarcoma from worsening by affecting cancerous cells.

Dosage and Administration

The dose of votrient that is prescribed will vary depending on the individual and type of cancer being treated. Follow all your healthcare provider’s instructions carefully and read packaging labels to ensure the best response during treatment. Do not change your dose or stop using this medication without talking to your healthcare provider first.

• Swallow tablets whole, do not crush
• Take on an empty stomach at least 1 hour before or 2 hours after eating
• If you need surgery, tell your surgeon beforehand that you take Votrient
• Store at room temperature away from children and pets

To treat kidney cancer and soft tissue sarcoma:

• Most adults take 800mg once daily
• Continue treatment until your condition improves
• If you miss a dose, do not take it if you have less than 12 hours until your next dose
• Adults should not take more than 800mg each day

Dose reductions due to reactions or impairments:

• Adults should reduce their daily dose to 400mg when reacting to kidney cancer treatment
• If reactions persist, doses can further reduce to 200mg taken once a day
• If adults react to treatment for soft tissue sarcoma, their dose should reduce to 600mg daily
• If patients continue to react, doses can reduce again to 400mg once a day
• Adults who have impaired liver function should reduce their doses to 200mg taken once daily

Side Effects

Votrient may cause some side effects to develop while affecting cancer cells to prevent their growth and spread. Speak to your healthcare provider to learn more about any symptoms that you may experience during treatment.

Common Votrient side effects:

• Nausea, vomiting, diarrhea, stomach pain
• Decreased appetite, weight loss
• Difficulty breathing
• Tumour, bone, or muscle pain
• Headache, tiredness
• Changes in hair or skin colour
• Changes in your ability taste

Serious Side Effects

Some more serious adverse reactions may occur when taking Votrient. Contact your healthcare provider right away if you develop any of the following symptoms:

• Headache, confusion, changes in mentality
• Vision changes
• Seizures
• Sudden chest pain, wheezing, dry cough
• Unusual bleeding or bruising
• Wounds or incisions that won’t heal
• Fast or pounding heartbeats, fluttering in your chest, sudden dizziness
• Heart problems (swelling, rapid weight gain, shortness of breath)
• Liver problems (nausea, vomiting, upper stomach pain, decreased appetite, tiredness, dark urine, jaundice)
• Signs of an infection (fever, runny nose, sore throat, body aches, skin sores, pain or burning during urination)
• Stomach bleeding (stomach pain or swelling, bloody or tarry stools, coughing blood, vomit that looks like coffee grounds)
• Heart attack symptoms (chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating)
• Stroke or blood clot symptoms (sudden numbness or weakness, severe headache, slurred speech, vision problems, chest pain, sudden shortness of breath, pain or cold in your arms or legs)
• Signs of tumour cell breakdown (tiredness, weakness, muscle cramps, nausea, vomiting, diarrhea, fast or slow heartbeat, tingling in your hands, feet, or around your mouth)

If you are 65 and older, you may be more likely to develop liver problems.

Seek immediate medical attention if you develop signs of dangerously high blood pressure which includes severe chest pain, severe headache, blurred vision, pounding in your neck or ears, anxiety, shortness of breath, or feeling faint.

Allergic Reactions

Do not take Votrient if you are allergic to pazopanib or any of the tablet ingredients. Call your healthcare provider immediately if you notice any of the following signs of an allergic reaction:

• Hives
• Difficulty breathing
• Swelling of your face, lips, tongue, or throat

Cautions

• Do not use Votrient if you have active liver disease because the medication could lead to serious or fatal liver problems. Contact your healthcare provider right away if you have any of the following symptoms: nausea, vomiting, upper stomach pain, decreased appetite, tiredness, easy bruising, dark urine, or jaundice.
• To ensure your safety when taking Votrient, tell your healthcare provider if you have ever had any of the following:
  • Liver disease
  • Heart disease, heart rhythm disorder
  • Long QT syndrome
  • High blood pressure
  • Blood clot or stroke
  • Thyroid disorder
  • Headaches, seizures, or problems with your vision
  • Hole or tear in your stomach or intestines
  • An abnormal passageway in your stomach or intestines
  • Stomach or intestinal bleeding
  • If you have undergone a surgical procedure within the past 7 days
• Votrient may cause a decrease in blood cells that help your body fight infections and clot your blood which can leave you susceptible to getting infections and bleeding more easily. Contact your healthcare provider if you notice unusual bruising or bleeding or any signs of an infection such as fever, chills, or body aches.
• Do not take Votrient if you are pregnant because the medication can cause harm to your unborn child. Use effective birth control during treatment and for at least 2 weeks after your final dose to prevent pregnancy. Your healthcare provider may require you to have a negative pregnancy test before starting treatment.
• Use condoms as contraceptives if you could impregnate a sexual partner during treatment with Votrient and for at least 2 weeks after your last dose because this medication could cause complications in your partner if they become pregnant.
• Do not breastfeed while taking Votrient and for at least 2 weeks after your final dose.
• Some drugs may interact with Votrient and cause unwanted reactions. Tell your healthcare provider about all the medications you take, including over the counter medicines, but especially any of the following:
  • Certain antibiotics
  • Antidepressant medications
  • Some HIV-1 medicines
  • Medications used to treat irregular heartbeats
  • Any medicine that contains simvastatin for high cholesterol
  • Stomach acid reducing medicines such as esomeprazole
• Avoid ingesting any grapefruit products during treatment with Votrient because it can cause an increase in adverse reactions.
• If your healthcare provider says you can take antacids during treatment with Votrient, do not use them within several hours of your dose. Avoid drugs that reduce your stomach acid because they can cause adverse reactions when taken with Votrient.

Form and Strength

This cancer medication is available in tablet form.

• Votrient tablet strength:
  • 200mg

The 200mg tablets are available in quantities of 60.

FAQ

Is Votrient a chemotherapy treatment?

Votrient is an oral cancer medication and not a chemotherapy treatment. This medicine targets cancer cells to prevent their growth and spread, helping your body fight your condition and reduce tumour growth. Speak with your healthcare provider for more information regarding how this medication works.

Does Votrient shrink tumours?

Votrient slows the growth and spread of cancer cells that cause kidney cancer and soft tissue sarcoma. Through these actions, this medication promotes progression-free survival and may help shrink cancerous tumours. Follow all your healthcare provider’s instructions during treatment for the best therapeutic response.

Resources:

1. https://www.drugs.com/votrient.html
2. https://www.hcp.novartis.com/products/votrient/
3. https://dailymed.nlm.nih.gov/dailymed/medguide.cfm?setid=eeaaaf38-fb86-4d9f-a19d-0f61daac2fd7
4. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=eeaaaf38-fb86-4d9f-a19d-0f61daac2fd7&type=display