Safely Buy Surmontil ( Trimipramine ) from Canada Prescriptions Plus.

Indications

Trimipramine is a tricyclic antidepressant that is used to treat symptoms of depression.

Trimipramine may also be used for purposes not listed in this medication guide.

Use and Dosage

Read the Medication Guide provided by your pharmacist before you start taking trimipramine and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually 1 to 3 times daily. If taking this medication once daily, take it at bedtime to decrease the risk of drowsiness. The dosage is based on your medical condition and response to treatment. Your doctor may start you at a low dose and gradually increase your dose. Follow your doctor’s instructions carefully.

This medication does not work right away. It may take 2 to 4 weeks before you experience the full benefits.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time(s) each day.

Keep taking this medication even if you feel well. Do not suddenly stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is abruptly stopped. Nausea, headache, and a feeling of being ill may also occur. Your dose may need to be gradually decreased.

Inform your doctor if your condition does not improve or if it worsens.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, such as mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Serious side effects include:

• Tunnel vision, eye pain or swelling, or seeing halos around lights
• A light-headed feeling, like you might pass out
• New or worsening chest pain, pounding heartbeats, or fluttering in your chest
• Confusion or unusual thoughts or behavior
• A seizure (convulsions)
• Painful or difficult urination
• Easy bruising or unusual bleeding
• Restless muscle movements in your eyes, tongue, jaw, or neck
• Fever, chills, sore throat, mouth sores, or feeling light-headed

Seek medical attention right away if you have symptoms of serotonin syndrome, such as agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Common side effects of trimipramine may include:

• Increased blood pressure
• Numbness or tingling in your hands or feet
• Dry mouth, nausea, or vomiting
• Rash or itching
• Breast swelling (in men or women)
• Abnormal liver function tests

This is not a complete list of side effects and others may occur.

Cautions

• Before taking trimipramine, tell your doctor or pharmacist if you are allergic to it; or to other tricyclic antidepressants (such as amitriptyline, or imipramine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
• Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood problems (such as agranulocytosis, thrombocytopenia), breathing problems (such as asthma, chronic obstructive pulmonary disorder-COPD), diabetes, electroshock therapy, personal or family history of glaucoma (angle-closure type), heart problems (such as recent heart attack, arrhythmias, coronary artery disease), intestinal problems (such as chronic constipation, ileus), kidney problems, liver problems, other mental/mood conditions (such as bipolar disorder, psychosis), family history of mental/mood conditions (such as suicide, bipolar disorder), seizures, conditions that may increase your risk of seizures (such as bulimia, organic brain disease, alcohol withdrawal), overactive thyroid (hyperthyroidism), problems urinating (urinary retention, enlarged prostate).
• Trimipramine may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, and fainting) that need medical attention right away.
• The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using trimipramine, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).
• Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/”water pills”) or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using trimipramine safely.
• This drug may make you dizzy, drowsy, or blur your vision. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
• Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
• This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness.
• This drug may rarely make your blood sugar rise, which can cause or worsen diabetes. If you have diabetes, check your blood sugar regularly as directed and share the results with your doctor. Tell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urination. Your doctor may need to adjust your diabetes medication, exercise program, or diet.
• Older adults may be more sensitive to the side effects of this drug, especially dizziness (more likely when standing up), drowsiness, confusion, constipation, trouble urinating or QT prolongation (see above). Drowsiness, dizziness, or confusion can increase the risk of falling.
• During pregnancy, this medication should be used only when needed. Infants born to mothers who have taken similar medications during pregnancy may develop trouble urinating, lethargy, shaking (tremors), and seizures. Discuss the risks and benefits with your doctor.
• Since untreated mental/mood problems (such as depression) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.
• It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Forms and Strengths

Surmontil is available in the following forms and strengths:

• Surmontil Tablet:
  • 12.5 mg
  • 25 mg
  • 50 mg
  • 75 mg
  • 100 mg

FAQ

What happens if I miss a dose?

Take the medicine as soon as you can but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention. An overdose of trimipramine can be fatal.

Overdose symptoms may include irregular heartbeats, severe drowsiness, confusion, hallucinations, agitation, stiff muscles, overactive reflexes, vomiting, feeling hot or cold, vision problems, feeling like you might pass out, seizures, or coma.

What should I avoid while taking trimipramine?

Drinking alcohol with trimipramine can cause side effects.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Trimipramine could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Resources:

1. https://www.webmd.com/drugs/2/drug-7031/surmontil-oral/details
2. https://www.drugs.com/mtm/trimipramine.html
3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/016792s034lbl.pdf