Safely Buy Steglujan ( Ertugliflozin/Sitagliptin ) from Canada Prescriptions Plus.

Indications

Steglujan is a diabetes medicine used to treat type 2 diabetes mellitus in adults.

This antidiabetic medication combines ertugliflozin, a sodium glucose co-transporter 2 (SGLT2) inhibitor, with sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor. These drugs help your body excrete glucose through your urine and reduce renal glucose production. Thanks to these actions, Steglujan can lower and manage your blood sugar levels to treat type 2 diabetes.

Dosage and Administration

The dose of Steglujan that is prescribed will vary depending on the individual being treated. Follow all instructions provided by your healthcare provider and read packaging labels carefully to ensure the best results during treatment with Steglujan. Do not change your dose on your own.

• Swallow tablet whole
• Take with or without food at the same time each morning
• Most adults start by taking 5mg ertugliflozin and 100mg sitagliptin once daily
• Doses can increase to 15/100mg if needed
• Adults should not take more than 15mg of ertugliflozin and 100mg sitagliptin once a day
• Patients switching from ertugliflozin monotherapy can take Steglujan with the same dose of ertugliflozin
• Store at room temperature away from children and pets

Side Effects

Steglujan may cause some side effects to develop while lowering your blood sugar levels. Speak with your healthcare provider to learn more about any symptoms that you may experience during treatment.

Common Steglujan side effects:

• Urinating more than usual
• Upset stomach, diarrhea
• Headache
• Cold symptoms such as stuffy nose, sneezing, sore throat

Older adults using Steglujan may be more likely to develop certain side effects during treatment.

Serious Side Effects

Some more serious adverse events may occur when taking Steglujan. Stop using this medication and contact your healthcare provider if you notice any of the following symptoms:

• New pain, tenderness, sores, ulcers, or infections in your legs or feet
• Severe or ongoing joint pain
• Little or no urination
• Severe autoimmune reaction (itching, blisters, breakdown of outer skin layer)
• Ketoacidosis (nausea, vomiting, stomach pain, confusion, unusual drowsiness, trouble breathing)
• Dehydration (dizziness, weakness, feeling faint or light-headed)
• Bladder infection (pain or burning when you urinate, increased urination, blood in your urine, fever, pelvis or back pain)
• Heart failure symptoms (shortness of breath, swelling in legs or feet, rapid weight gain)
• Symptoms of pancreatitis (severe upper stomach pain spreading to your back, nausea, vomiting)

Seek immediate medical attention if you develop any signs of a rare but serious infection of the genitals. Symptoms include burning, itching, odour, unusual discharge, pain, tenderness, redness, or swelling of the genital or rectal area, fever, ill-feeling.

Allergic Reactions

Do not use Steglujan if you are allergic to ertugliflozin, sitagliptin, or any of the other listed tablet ingredients. If you notice signs of an allergic reaction, stop using this medication and contact your healthcare provider.

Steglujan allergy symptoms may include:

• Hives, rash, itching
• Difficulty breathing
• Swelling in face or throat
• Fever
• Sore throat
• Burning eyes
• Skin pain
• Blistering or peeling skin

Cautions

Do not take Steglujan if you have ever had any of the following:

• Severe kidney problems
• End stage renal disease
• Are on dialysis

Steglujan may cause your pancreas to become inflamed which can become severe and may lead to death. Your risk of developing pancreatitis may be higher if you have ever had the condition before or if you have a history of alcoholism, kidney problems, gallstones, or high levels of triglycerides. Contact your healthcare provider if you develop severe stomach pain spreading to your back with or without vomiting.

This diabetes medication may increase your risk of needing lower limb amputations, especially if you have a history of amputation, have had blocked or narrowed blood vessels, have damage to your leg nerves, or have had diabetic foot ulcers or sores before.

In rare cases, Steglujan has been found to cause serious infections in the penis or vagina. Seek medical attention if you notice any of the following symptoms: burning, itching, odour, discharge, pain, tenderness, redness or swelling of genital or rectal area, fever, or general ill-feeling.

To ensure your safety when taking Steglujan, tell your healthcare provider if you have ever had any of the following:

• Type 1 diabetes or diabetic ketoacidosis
• Kidney or liver problems
• Problems with your pancreas including pancreatitis or surgery
• History of urinary tract infections or problems urinating
• History of amputation
• Blocked or narrowed blood vessels
• Damaged nerves in your legs
• Diabetic ulcer or sores in your feet
• Have an upcoming surgery

Avoid drinking large amounts of alcohol while taking Steglujan because it can cause an increase in adverse reactions.

Tell your healthcare provider if you are pregnant before taking Steglujan. It is important to control your blood sugar levels during pregnancy, but Steglujan may cause complications if used during the second or third trimesters.

Do not breastfeed while taking Steglujan.

Steglujan can cause you to become dehydrated more easily which can lead to dizziness or feeling weak, especially when you stand from a seated or laying position.

Some drugs can interact with Steglujan and cause adverse reactions. Tell your healthcare provider about all the medicines you take, including over the counter medications, but especially any of the following:

• Insulin or insulin secretagogue
• Lithium

Steglujan is not an approved treatment for anyone under the age of 18.

Form and Strength

This diabetes medication is available in the form of film coated tablets.

Steglujan tablet strengths:

• 5mg ertugliflozin/100mg sitagliptin
• 15/100mg

The 5/100mg and 15/100mg strength Steglujan tablets are both available in quantities of 28 and 84.

FAQ

Should Steglujan be taken before or after food?

It is recommended that you take your daily dose of Steglujan in the morning at the same time each day. The medication can be taken with or without food, meaning you can take your doses whenever and however is most convenient for you. Make sure that you follow all your healthcare provider’s instructions for the best therapeutic results.

What are the side effects of Steglujan?

Steglujan is most commonly reported to cause mild side effects such as upset stomach, diarrhea, increased urination, headache, and cold symptoms. Speak with your healthcare provider to learn more about these reactions and other more serious effects that could occur. Follow all directions provided by your healthcare provider to help minimize adverse reactions.

Resources:

1. https://www.drugs.com/steglujan.html
2. https://www.merck.com/product/usa/pi_circulars/s/steglujan/steglujan_mg.pdf
3. https://www.merck.com/product/usa/pi_circulars/s/steglujan/steglujan_pi.pdf