Safely Buy Rifadin ( Rifampin ) from Canada Prescriptions Plus.

Indications

Rifadin is an antibiotic medication used to treat tuberculosis and prevent the development of bacterial meningitis.

Rifampin is an anti-tuberculous drug that inhibits DNA-dependent bacterial RNA polymerase in organisms susceptible to tuberculosis. By blocking this RNA polymerase, Rifadin helps treat and prevent tuberculosis by slowing and stopping the spread of bacteria involved in tuberculosis as well as meningitis.

Uses and Dosage

The dose of Rifadin that is prescribed will vary depending on the individual and bacterial condition being treated. Follow all your doctor’s instructions and read packaging labels carefully to ensure the best results during treatment with rifampin.

• Swallow capsule whole, do not crush or chew
• Take on an empty stomach at least 1 hour before breakfast
• Most adults take 600mg once daily to treat tuberculosis
• Children with tuberculosis should take 10 to 20mg/kg without exceeding 600mg per day
• When treating pulmonary tuberculosis, Rifadin should be taken with at least one other anti-tuberculous drug
• To prevent meningitis, adults should take 600mg every 12 hours for two days
• Children should take 10mg/kg up to a total of 600mg every 12 hours for two days
• Take Rifadin exactly as directed by your doctor for the length of time they prescribe
• Store at room temperature away from children and pets

Side Effects

Rifadin may cause some side effects to develop while killing and inhibiting the spread of bacteria that causes tuberculosis and meningitis. Speak with your doctor if you have any concerns regarding reactions that you may experience when taking rifampin.

Common Rifadin side effects:

• Diarrhea
• Drowsiness, tiredness, weakness
• Gas
• Headache
• Upset stomach, vomiting
• Decreased appetite
• Heartburn
• Stomach cramps
• Orange or red bodily fluids

Serious Side Effects

Some more serious adverse reactions may occur when taking rifampin. Stop using Rifadin and contact your doctor if you develop any of the following side effects:

• Kidney problems (difficulty passing urine, changes in urination, blood in urine, unusual weight gain)
• Dizziness, fainting
• Flu-like symptoms
• Fever, chills, sore throat
• Unexplained bruising or bleeding
• Tiredness or weakness
• Swollen glands
• Joint pain or swelling
• Muscle pain or weakness
• Shortness of breath
• Chest pain
• Cough
• Increased sweating
• Unusual heartbeat
• Swelling in arms or legs
• Purple spots or skin redness
• Change in balance
• Confusion, inability to focus, changes in behaviour
• Menstrual changes
• Change in eyesight, eye pain or irritation
• C diff-associated diarrhea (stomach pain, cramps, very loose, watery or bloody stool)

Allergic Reactions

Do not take Rifadin if you are allergic to rifampin, other rifamycin drugs, or any of the other listed capsule ingredients. If you notice any signs of an allergic reaction, stop using this anti-tuberculous medication and call your doctor.

Rifadin allergy symptoms may include:

• Hives, itching
• Red, swollen, blistered, or peeling skin
• Fever, wheezing
• Difficulty breathing, swallowing, or talking
• Swelling of face, lips, tongue, or throat

Cautions

Do not use Rifadin if you have reduced bilirubin excretion.

Rifadin should not be administered to premature or newborn babies because their liver cannot function fully.

Do not drink alcohol while taking Rifadin because it can increase adverse reactions and cause damage to your liver.

To ensure your safety when taking Rifadin, tell your doctor if you have ever had any of the following:

• Liver problems
• Diarrhea, colitis symptoms
• Toxic megacolon
• Perforated colon
• If you take anticoagulants to prevent blood clots

Rifampin and other related drugs may cause your teeth and bodily fluids to discolour. This includes urine, stool, saliva, sweat, and tears turning yellow, orange, red, or brown. These reactions should resolve after treatment with Rifadin is discontinued.

Rifadin has been reported to cause liver dysfunction, especially when taking by patients with liver disease or those who are receiving other medications that may cause damage to the liver.

Antibacterial drugs including rifampin have been associated with the development of C-difficile associated disease which can result in mild diarrhea to fatal colitis.

Some drugs may interact with rifampin and cause unwanted reactions. Tell your doctor about all the medications you take, including over the counter medicines, but especially any of the following:

• Combined saquinavir and ritonavir
• Antiviral medications (atazanavir, darunavir, fosamprenavir, tipranavir)
• Anticonvulsant drugs (phenytoin and others)
• Digitoxin
• Antiarrhythmic medicines (disopyramide, mexiletine, quinidine, and others)
• Oral anticoagulant drugs
• Antifungal medications (fluconazole, itraconazole, ketoconazole, and others)
• Chloramphenicol
• Clarithromycin
• Corticosteroid drugs
• Cyclosporine
• Hormonal contraceptives
• Diazepam
• Doxycycline
• Tricyclic antidepressants
• Zidovudine

Rifampin can reduce the efficacy of hormonal birth control methods. Ensure that you use non-hormonal contraceptive methods during treatment with Rifadin to prevent pregnancy.

Tell your doctor if you are pregnant or planning to become pregnant while taking Rifadin. The effects of rifampin on unborn babies are unclear but it should not be used during pregnancy.

Do not breastfeed while taking Rifadin. Rifampin can cross into breastmilk and affect your nursing child.

Form and Strength

This anti-tuberculous medication is available in the form of capsules.

Rifadin capsule strengths:

• 150mg
• 300mg

The 150 and 300mg strength Rifadin capsules are both available in quantities of 100.

FAQ

What not to do while taking Rifadin?

Rifadin can cause harm to your liver so you should not drink alcohol to avoid liver damage. You should also not rely on hormonal methods of birth control while taking this medication because antibiotics including rifampin can reduce the efficacy of hormonal birth control.

Should Rifadin be taken on an empty stomach?

Yes, you should take your doses of Rifadin on an empty stomach at least one hour before eating a meal. It is recommended that you take your dose in the morning before breakfast. Taking this medication on an empty stomach helps your body better absorb rifampin into your system.

Resources:

1. https://pdf.hres.ca/dpd_pm/00040693.PDF
2. https://www.drugs.com/cdi/rifadin.html
3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/050420s073,050627s012lbl.pdf