Safely Buy Proamatine ( Midodrine ) from Canada Prescriptions Plus.

Indications

Proamatine is a blood pressure medication used to treat hypotension (low blood pressure).

Midodrine is a peripheral alpha-1 adrenoceptor agonist that increases standing systolic blood pressure and improves orthostatic symptoms by stimulating adrenergic receptors that affect blood flow. This action allows Proamatine to raise your overall standing blood pressure and manage hypotension.

This blood pressure medication is a safe and effective form of treatment for hypotension. Studies have found Proamatine to be as effective as dihydroergotamine and other sympathomimetic agents while offering a lower incidence of adverse events. Midodrine’s most common side effects are often mild and can be controlled.

Uses and Dosage

The dose of Proamatine will vary depending on the individual being treated. Follow all your doctor’s instructions and read packaging labels carefully when using midodrine for the best results.

• Swallow tablets whole
• Take with or without food
• Take your last dose 3 to 4 hours before going to bed
• Most adults are recommended to take 10mg three times a day
• Doses tend to be taken in intervals of 4 hours
• Adults should take their Proamatine doses no less than 3 hours apart to avoid hypertension
• Doses are recommended to be taken upon waking, midday, and late afternoon
• Adults should not take more than 30mg at once
• You will need to monitor your supine and standing blood pressure regularly
• Your head may need to remain elevated while laying down or sleeping
• Store at room temperature away from children and pets

Side Effects

Proamatine may cause some side effects to develop while raising your blood pressure levels. Speak with your doctor for more information regarding any symptoms that you may encounter when taking midodrine.

Common Proamatine side effects:

• Chills, goosebumps
• Numbness, tingling, itching
• Headache, dizziness, tiredness
• Nausea
• Increased urination, painful or difficult urination, sudden urge to urinate

Serious Side Effects

Some more serious adverse reactions may occur when taking midodrine. Stop using Proamatine and call your doctor if you develop any of the following symptoms:

• Severely slow heart rate (weak pulse, severe dizziness or light-headedness)
• Dangerously high blood pressure (severe headache, pounding in your ears, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeat, seizure)

Allergic Reactions

Do not use Proamatine if you are allergic to midodrine or any of the other listed tablet ingredients. If you notice signs of an allergic reaction, stop using this medication and contact your doctor right away.

Proamatine allergy symptoms may include:

• Hives
• Difficulty breathing
• Swelling of face, lips, tongue, or throat

Cautions

Proamatine should only be used if you have severely low blood pressure because midodrine can raise your blood pressure even while you are resting.

Avoid taking Proamatine within 3 hours before your bedtime, because if not midodrine could cause your blood pressure to rise too much while sleeping.

Ask your doctor before taking any over-the-counter diet pills, cough medicine, or cold medications that contain phenylephrine or pseudoephedrine. These drugs can raise your blood pressure.

Do not take Proamatine if you have any of the following:

• Severe heart disease
• Overactive thyroid
• Adrenal gland tumor
• If you are unable to urinate
• If you have high blood pressure even while lying down

To ensure your safety when taking Proamatine, tell your doctor if you have any of the following:

• Diabetes
• Glaucoma or a history of vision problems
• Liver disease
• History of kidney disease

Consult with your doctor before using Proamatine if you are pregnant or breastfeeding. It is unclear whether midodrine will affect an unborn or nursing baby.

Some drugs may interact with midodrine and cause unwanted adverse reactions. To avoid this, tell your doctor about all the medications that you take, including over the counter medicines, but especially any of the following:

• Digoxin, digitalis, droxidopa, fludrocortisone
• Antidepressant
• Asthma medicine
• Heart or blood pressure medication
• Migraine medication
• Thyroid medicine like levothyroid
• Drugs for high blood pressure or a prostate disorder (prazosin, terazosin, doxazosin)
• An MAO inhibitor (isocarboxazid, linezolid, methylene blue injection, and others)

Form and Strength

This blood pressure medication is available in tablet form.

Proamatine tablet strengths:

• 2.5mg
• 5mg
• 10mg

All three Proamatine tablet strengths are available in quantities of 100.

FAQ

What to avoid when taking Proamatine?

You should avoid taking Proamatine less than 3 hours before going to sleep because midodrine can cause your blood pressure to increase even while you are lying down and could lead to supine hypertension.

What are the contraindications for Proamatine?

Proamatine is contraindicated in those with severe heart disease, liver disease, urinary retention, an adrenal gland tumor, and who have an overactive thyroid gland. This blood pressure medication is generally safe and well-tolerated in other patients without these underlying conditions. Side effects are often mild and can be controlled by lowering the midodrine dosage.

Resources:

1. https://pubmed.ncbi.nlm.nih.gov/9467688/
2. https://pubmed.ncbi.nlm.nih.gov/2480881/
3. https://www.drugs.com/cons/proamatine.html
4. https://www.drugs.com/mtm/midodrine.html
5. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9e8874f0-ad2e-41ce-8a35-bed819615a5d