Safely Buy Depakote CR ( Divalproex ) from Canada Prescriptions Plus.

Indications

Depakote CR (controlled release) is a formulation of the medication divalproex sodium.

Depakote CR is used to treat various conditions, including seizure disorders, and mental/mood conditions (such as the manic phase of bipolar disorder), and to prevent migraine headaches.

Divalproex sodium is an effective anticonvulsant, antimanic, and migraine prophylaxis agent. It works by calming overactive nerves in the body.

Depakote CR is designed to release the medication slowly over time, providing a steady and consistent level of the drug in the body.

Use and Dosage

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Drink plenty of water while you are taking this medication. Your dose may need to be changed if you do not get enough fluids each day.

Swallow the capsule or tablet whole and do not crush, chew, break, or open it.

If you cannot swallow a sprinkle capsule whole, open it and sprinkle the medicine into a spoonful of pudding or applesauce. Swallow the mixture right away. Do not save it for later use.

You may need frequent blood tests.

If you need surgery, tell the surgeon ahead of time that you are using divalproex sodium.

In case of emergency, wear or carry medical identification to let others know you use divalproex sodium.

Do not stop using divalproex sodium suddenly, even if you feel fine. Stopping suddenly may cause a serious, life-threatening type of seizure. Follow your doctor’s instructions about tapering your dose.

Side Effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficulty breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Call your doctor at once if the person taking divalproex sodium has signs of liver or pancreas problems, such as loss of appetite, upper stomach pain (that may spread to your back), ongoing nausea or vomiting, dark urine, swelling in the face, or jaundice (yellowing of the skin or eyes).

Report any new or worsening symptoms to your doctor, such as mood or behavior changes, depression, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have any of these other side effects:

• Easy bruising, unusual bleeding (nose, mouth, or gums), purple or red pinpoint spots under your skin
• Fever, swollen glands, mouth sores
• Confusion, tiredness, cold feeling, vomiting, change in your mental state
• Severe drowsiness
• Worsening seizures

Common side effects of divalproex sodium may include:

• Nausea, vomiting, stomach pain, diarrhea, constipation
• Headache, back pain
• Dizziness, drowsiness, weakness, tremors
• Memory problems, mood changes, trouble sleeping
• Bruising or bleeding
• Runny nose, sore throat, cough, wheezing, trouble breathing
• Fever, flu symptoms
• Problems with walking or coordination
• Swelling in your hands or feet
• Blurred vision, double vision, unusual eye movements
• Ringing in your ears
• Rash, hair loss
• Changes in weight or appetite

This is not a complete list of side effects and others may occur.

Cautions

• You should not use divalproex sodium if you have liver disease, a urea cycle disorder, or a genetic disorder such as Alpers’ disease or Alpers-Huttenlocher syndrome.
• Do not start or stop taking divalproex sodium during pregnancy without your doctor’s advice. Divalproex sodium may harm an unborn baby, but having a seizure during pregnancy could harm both mother and baby. Do not use divalproex sodium to prevent migraine headaches if you are pregnant.
• Divalproex sodium can cause liver failure that may be fatal, especially in children under age 2 and in people with liver problems caused by certain genetic disorders.
• Call your doctor at once if the person taking this medicine has signs of liver or pancreas problems, such as loss of appetite, upper stomach pain (that may spread to your back), ongoing nausea or vomiting, dark urine, swelling in the face, or jaundice (yellowing of the skin or eyes).
• Do not stop using divalproex sodium without your doctor’s advice. Stopping suddenly may cause a serious, life-threatening type of seizure.

Forms and Strengths

Depakote CR is available in the following forms and strengths:

• Divalproex Controlled Release Tablet:
  • 500 mg

FAQ

What happens if I miss a dose?

Take the medicine as soon as you can but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention.

What should I avoid while taking divalproex sodium?

Drinking alcohol may increase certain side effects of divalproex sodium.

Avoid driving or hazardous activity until you know how divalproex sodium will affect you. Your reactions could be impaired.

Resources:

1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021168s016lbl.pdf
2. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0dc024ce-efc8-4690-7cb5-639c728fccac
3. https://www.drugs.com/mtm/divalproex-sodium.html#before-taking
4. https://reference.medscape.com/drug/depakote-divalproex-sodium-999832