Safely Buy Cymbalta ( Duloxetine ) from Canada Prescriptions Plus.

Indications

Cymbalta is an antidepressant used to treat symptoms of depression, major depressive disorder (MDD), and generalized anxiety disorder (GAD). This medication has also been approved for relieving pain caused by diabetic peripheral neuropathy, fibromyalgia, and musculoskeletal pain such as that caused by osteoarthritis.

Duloxetine is a potent serotonin and norepinephrine (NE) reuptake inhibitor. It helps relieve symptoms by stopping chemicals such as serotonin and norepinephrine from being absorbed too soon.

Uses and Dosages

Doses of Cymbalta will vary depending on the person and condition being treated. Follow your doctor’s instructions when taking; do not take more than the amount prescribed.

• Take with or without food
• Swallow the delayed release capsules, do not chew or crush
• For MDD, adults usually take between 40 and 60mg a day
• For GAD, adults usually take up to 60mg daily
• For pain, adults usually take up to 60mg each day
• Store away from moisture and heat at room temperature

Side Effects

Because this medication affects chemicals in your brain, Cymbalta may cause some side effects. Speak with your doctor for more information and advice concerning any side effects that you may encounter.

Common Cymbalta side effects include:

• Drowsiness
• Nausea
• Constipation
• Loss of appetite
• Dry mouth
• Increased sweating

Speak with your doctor if you notice sudden mood or behavior changes such as new or worse depression or anxiety, panic attacks, trouble sleeping, or feeling impulsive, irritable, agitated, hostile, aggressive, more active or talkative, or if you have suicidal thoughts.

Serious Side Effects

Some more serious side effects may occur when taking Cymbalta. Stop using and speak with your doctor if you notice any of the following:

• Pounding heartbeats or fluttering in your chest
• Light-headed feeling like you might pass out
• Easy bruising
• Unusual bleeding
• Changes in vision
• Painful or difficult urination
• Liver problems (upper stomach pain on the right side, itching, dark urine, jaundice)
• Low blood sodium (headache, confusion, memory or thinking problems, weakness, feeling unsteady)
• Manic episodes (racing thoughts, increased energy, decreased need for sleep, risk-taking behavior, agitation, being talkative)

Seek immediate medical attention if you notice signs of serotonin syndrome. Symptoms include: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Allergic Reactions

Do not take Cymbalta if you are allergic to duloxetine. Stop taking and seek immediate medical help if you notice signs of an allergic reaction.

Cymbalta allergy symptoms may include:

• Hives
• Difficulty breathing
• Swelling in face or throat
• Fever
• Sore throat
• Burning eyes
• Skin pain
• Red or purple rash
• Blistering or peeling skin

Cautions

Do not take this medication 5 days before or 14 days after taking an MAO inhibitor because the drugs could interact and cause dangerous side effects. These include isocarboxazid, linesolid, methylene blye injection, phenelzine, or tranylcypromine.

Consult with your doctor before taking and tell them about other medicines you take, especially opioid medications or other ones for depression, Parkinson’s disease, migraines, serious infections, or prevention of nausea and vomiting. These could interact with duloxetine and cause serotonin syndrome.

Ask your doctor before using a nonsteroidal anti-inflammatory drug when taking Cymbalta because they could cause you to bruise or bleed more easily. These drugs include aspirin, ibuprofen, naproxen, and others.

Do not give Cymbalta to children younger than 7.

Some young people may notice an increase in suicidal thoughts when they first start taking Cymbalta and other antidepressants. Keep track of your moods, behaviors, and symptoms.

Avoid taking Cymbalta or other SNRI antidepressants during late pregnancy to prevent serious complications with your baby. Consult with your doctor for the best course of action.

If you are breastfeeding and notice drowsiness, feeding problems, and slow weight gain in your baby, tell your doctor.

Form and Strength

This medication is available in delayed release capsules.

Cymbalta delayed released capsule strengths:

• 20mg
  • Quantities of 60
  • 100
• 30mg
  • Quantities of 28
  • 56
  • 84
  • 100
• 40mg
  • Quantities of 50
  • 100
• 60mg
  • Quantities of 28
  • 84

FAQ

How long does it take for Cymbalta to work?

This medication must work into your system so it may take up to 6 or 8 weeks to show full effects. Some symptoms may improve in the first two weeks such as sleep, energy, or appetite, but others including depressed mood and lack of interest in activities may take up to the full 8 weeks to resolve.

Does Cymbalta cause weight gain?

Cymbalta is more likely to cause weight loss in the first 8 or 9 weeks of treatment because it can produce a loss of appetite. After 8 months, modest weight gain may occur. These changes are usually minimal.

How do you sleep while taking Cymbalta?

A common side effect of Cymbalta is insomnia. For some, this improves after the first few weeks of taking it, but if not, you can take your full dose once a day in the mornings.

Resources:

1. https://pubmed.ncbi.nlm.nih.gov/30838456/
2. https://www.drugs.com/cymbalta.html
3. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2f7d4d67-10c1-4bf4-a7f2-c185fbad64ba