Safely Buy Agrylin ( Anagrelide ) from Canada Prescriptions Plus.

Indications

Agrylin is a blood medication used to treat thrombocythemia or thrombocytosis, a condition that occurs when your body produces too many platelet cells in your blood. This medication is also used to treat myeloproliferative neoplasms and reduce the risk of thrombosis.

Anagrelide is a platelet reducing drug that inhibits aspects of platelet cells to reduce platelet levels. Thanks to this effect, Agrylin helps reduce your body’s production of platelet cells and prevent the risk of thrombo-hemorrhagic events.

Form and Strength

The dose of Agrylin that is prescribed will vary depending on the individual and thrombotic condition being treated. Follow all directions of use given by your healthcare provider and read packaging labels carefully to ensure the best response. Do not use more or less than prescribed for a different length of time than recommended.

• Swallow capsules whole, do not crush or chew
• Take at the same times each day
• Can be taken with or without food
• Most adults start treatment by taking 0.5mg four times daily or 1mg twice a day
• After at least one week of treatment, doses can be titrated for effective reduction of platelet counts by 0.5mg a day in weekly increments
• Maintenance doses tend to range from 1.5 to 3mg a day
• Adults should not take more than 2.5mg in a single dose or exceed a total of 10mg a day
• Platelet counts should be monitored monthly during treatment with Agrylin
• Tell your surgeon you take Agrylin before undergoing any surgical procedures
• Do not suddenly stop using Agrylin, even if you feel well
• Store at room temperature away from children and pets

Side Effects

Agrylin may cause some side effects to develop during treatment while lowering your platelet cell count. Speak to your healthcare provider for more information regarding any symptoms that you may encounter during treatment.

Common Agrylin side effects:

• Fast heartbeats, chest pain, trouble breathing
• Numbness, tingling, burning pain
• Headache, weakness, dizziness
• Stomach pain, gas, indigestion
• Decreased appetite
• Nausea, vomiting, diarrhea
• Swelling of your hands or feet
• Fever, cough, general ill-feeling
• Back pain
• Rash, itching

Serious Side Effects

Some more serious adverse reactions may occur during treatment with Agrylin. Contact your healthcare provider right away if you develop any of the following symptoms:

• Easy bruising or bleeding
• Signs of stomach bleeding (bloody or tarry stools, coughing blood, vomit that looks like coffee grounds)
• Chest pain or pressure
• Fast or pounding heartbeats, fluttering sensation in your chest, sudden dizziness
• Shortness of breath
• Swelling of your lower legs
• Blue colour in your lips or skin

Allergic Reactions

Do not take Agrylin if you are allergic to anagrelide. Call your healthcare provider immediately if you develop any of the following signs of an allergic reaction:

• Hives
• Trouble breathing
• Swelling of your face, lips, tongue, or throat

Cautions

• To ensure your safety when taking Agrylin, tell your healthcare provider if you have ever had any of the following conditions:
  • Bleeding issues
  • Long QT syndrome
  • Heart or lung problems
  • Liver disease
  • Electrolyte imbalance
• Tell your healthcare provider if you are pregnant or plan to become pregnant before using Agrylin. It is unclear how this medication may impact you and your child if used during pregnancy.
• Do not breastfeed while taking Agrylin
• Agrylin may affect your ability to have children. Speak with your healthcare provider to learn more about your risk.
• Do not take aspirin while using Agrylin unless directed to do so by your healthcare provider. Ensure that you closely follow how much aspirin your healthcare provider says you can take.
• Ask your healthcare provider before taking any medications to relieve pain, fevers, inflammation, or cold or flu symptoms. These medicines can contain aspirin and similar ingredients which can increase your risk of bleeding.
• Agrylin may cause you to develop a serious heart problem. Your risk may be higher if you also take certain medications for infections, asthma, heart problems, blood pressure, depression, mental illness, cancer, malaria, or HIV.
• Some other drugs may interact with Agrylin and cause adverse reactions. Tell your healthcare provider about all the medicines you use, but especially any of the following:
  • Antidepressants
  • Medications used to improve blood flow
  • Blood thinners or other medications used to treat or prevent blood clots
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Agrylin is not an approved form of treatment for anyone under the age of 7.

Form and Strength

This platelet reducing medication is available in capsule form.

• Agrylin capsule strength:
  • 0.5mg

The 0.5mg Agrylin capsules are available in quantities of 100.

FAQ

Should I take Agrylin with or without food?

You can take your doses of Agrylin with or without food. When taken with food, your absorption of the medicine is slightly decreased but not enough to impact its effect on reducing your platelet counts. Follow all instructions given by your healthcare provider and take your doses at the same times each day for the best therapeutic results.

How long does it take Agrylin to work?

Agrylin is quickly absorbed into your system and should begin to lower your platelet counts within 7 to 14 days after you have reached the proper dose required for you. Doses should increase in small amounts every week until your platelet levels are adequately lowered.

Resources:

1. https://www.drugs.com/mtm/agrylin.html
2. https://www.healthlinkbc.ca/medications/anagrelide-oral
3. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=cb960074-99c1-4a73-941f-f0644a7ec219&type=display
4. https://assets-dam.takeda.com/image/upload/v1679321565/legacy-dotcom/siteassets/en-ca/home/what-we-do/our-medicines/product-monographs/agrylin/Agrylin-PM-EN.pdf