Safely Buy Corlanor ( Ivabradine ) from Canada Prescriptions Plus.

Indications

Corlanor is a medication used to treat chronic heart failure in adults with symptoms, to reduce their risk of hospitalization for worsening heart failure.

Corlanor works selectively and specifically inhibits the cardiac pacemaker current, slowing the heart rate. Corlanor is also used to treat stable symptomatic heart failure caused by dilated cardiomyopathy among pediatric patients who are 6 months of age and above.

Corlanor is classified as a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker. This type of medication mainly works by regulating heart rate and prolonging diastolic time.

Use and Dosage

Take Corlanor medication exactly as advised by the doctor. This is typically taken two times a day (preferably at equal intervals) by mouth with food. Swallow the tablet and drink fluids right after. You may cut the scored tablets in equal halves.

The doctor may initiate this treatment at a low dose and carefully increase the dose to minimize the risk of side effects.

Starting dose is 5 mg twice daily. After 2 weeks of treatment, adjust the dose based on heart rate. The maximum dose is 7.5 mg twice daily. In patients with conduction defects or in whom bradycardia could lead to hemodynamic compromise, initiate dosing at 2.5 mg twice daily.

Side Effects

Common side effects include:

• Dizziness or lightheadedness
• High blood pressure
• Tiredness
• Slow heart rate or bradycardia
• Temporary vision disturbance, like seeing flashes of light

If any of the adverse effects above persist or worsen, you should consult your doctor about it.

Serious Side Effects include:

• Irregular heartbeat or atrial fibrillation
• Fainting
• Unusual weakness or fatigue
• Continuous high blood pressure

These severe adverse effects must be communicated to your healthcare provider immediately.

Cautions

• Fetal toxicity: Females should use effective contraception.
• Monitor patients for atrial fibrillation.
• Monitor heart rate decreases and bradycardia symptoms during treatment.
• Not recommended in patients with 2nd-degree AV block.
• Corlanor is contraindicated in patients with:
  • Acute decompensated heart failure
  • Irregular heartbeat
  • Pacemaker
  • Sick sinus syndrome
  • Heart block
  • Low blood pressure
  • Liver problems

Corlanor should be avoided by women who are pregnant or are planning to conceive. This medication may harm or cause undesirable effects on unborn babies. Ivabradine is known to pass into breast milk and should be avoided in breastfeeding women.

Form and Strengths

Corlanor is available in the following form and strengths:

• Corlanor Tablet:
  • 5mg
• Ivabradine Film Coated Tablet:
  • 5mg
  • 7.5mg

FAQ

Does Corlanor work immediately?

It may take a short while for Corlanor’s oral medication to work. It may start working within two hours when taken with food.

What should I avoid while taking Corlanor?

While taking Corlanor medication do not consume grapefruit, or anything with grapefruit in it, as this fruit can increase the level of ivabradine in the body. Alcohol intake must also be limited because it can trigger certain side effects.

How much does Corlanor lower heart rate?

The dosage of Corlanor is primarily based on the patient’s targeted heart rate. In adults, this medication should reduce the heart rate to 50-60 beats per minute.

Resources:

1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/206143orig1s002lbl.pdf
2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671466/
3. https://www.corlanor.com/