Safely Buy Prempro Low Dose ( Medroxyprogesterone/Estrogen ) from Canada Prescriptions Plus.

Indications

Prempro Low Dose is a medication that combines conjugated estrogens and medroxyprogesterone acetate in lower doses and is used to treat moderate to severe hot flashes associated with menopause.

Prempro Low Dose is primarily used to relieve hot flashes, a common symptom experienced by women during menopause.

Use and Dosage

Read the Patient Information Leaflet if available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once daily. You may take it with food or right after a meal to prevent stomach upset.

The dosage is based on your medical condition and response to treatment.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Follow your dosing schedule carefully. Do not increase your dose or take this medication more often or for a longer time than directed.

Tell your doctor if your condition does not improve or if it worsens.

Side Effects

Get emergency medical help if you have signs of an allergic reaction to Prempro: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• Heart attack symptoms – chest pain or pressure, pain spreading to your jaw or shoulder, nausea, or sweating
• Signs of a stroke – sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, or problems with vision or balance
• Signs of a blood clot – sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, or pain or warmth in one or both legs
• Swelling or tenderness in your stomach
• Jaundice (yellowing of the skin or eyes)
• Memory problems, confusion, or unusual behavior
• Unusual vaginal bleeding or pelvic pain
• A lump in your breast
• High levels of calcium in your blood – nausea, vomiting, constipation, increased thirst or urination, muscle weakness, bone pain, or lack of energy

Common Prempro side effects may include:

• Nausea, gas, or stomach pain
• Headache or back pain
• Depression or weakness
• Breast pain
• Itching or thinning scalp hair
• Vaginal itching or discharge, changes in your menstrual periods, and breakthrough bleeding

This is not a complete list of side effects and others may occur.

Cautions

• Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
• Before using this medication, tell your doctor or pharmacist your medical history, especially of: vaginal bleeding of unknown cause, certain cancers (such as breast cancer, cancer of the uterus/ovaries), blood clots, stroke, heart disease (such as heart attack), liver disease, kidney disease, family medical history (especially breast lumps, cancer, blood clots), family or personal history of a certain swelling disorder (angioedema), blood clotting disorders (such as protein C or protein S deficiency), high blood pressure, diabetes, high blood cholesterol/triglyceride levels, obesity, lupus, underactive thyroid (hypothyroidism), mineral imbalance (low or high level of calcium in the blood), a certain hormone problem (hypoparathyroidism), uterus problems (such as fibroids, endometriosis), gallbladder disease, asthma, seizures, migraine headaches, a certain blood disorder (porphyria), mental/mood disorders (such as dementia, depression).
• Do not smoke or use tobacco. Estrogens combined with smoking further increases your risk of stroke, blood clots, high blood pressure, and heart attack, especially in women older than 35.
• Tell your doctor if you just had or will be having surgery, or if you will be confined to a chair or bed for a long time (such as a long plane flight). These conditions increase your risk of getting blood clots, especially if you are using an estrogen product. You may need to stop this medication for a time or take special precautions.
• This medication may cause blotchy, dark areas on your face and skin (melasma). Sunlight may worsen this effect. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors.
• If you are nearsighted or wear contact lenses, you may develop vision problems or trouble wearing your contact lenses.
• Contact your eye doctor if these problems occur.
• This medication should not be used during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor right away.
• This medication passes into breast milk. It may reduce the quality and amount of breast milk produced. Consult your doctor before breast-feeding.

Forms and Strengths

Prempro Low Dose is available in the following forms and strengths:

• Prempro Low Dose Tablet:
  • 1.5/0.3 mg
  • 5/0.625 mg

FAQ

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra Prempro to make up for the missed dose.

What happens if I overdose?

Seek emergency medical attention.

What to avoid?

Avoid smoking. It can greatly increase your risk of blood clots, stroke, or heart attack while using this medicine.

Grapefruit and grapefruit juice may interact with conjugated estrogens and medroxyprogesterone and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor.

Resources:

1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020527s046lbl.pdf
2. https://www.webmd.com/drugs/2/drug-5365/prempro-oral/details
3. https://www.drugs.com/prempro.html#side-effects