Safely Buy Vytorin ( Ezetimibe/Simvastatin ) from Canada Prescriptions Plus.

Indications

Vytorin is an antihyperlipidemic medication used to lower cholesterol and triglyceride levels while raising good cholesterol to treat hyperlipidemia.

This cholesterol medicine combines ezetimibe, a cholesterol absorption inhibitor, and simvastatin, an HMG-CoA reductase inhibitor statin drug. These medications reduce the synthesis and intestinal absorption of total cholesterol and bad cholesterol as well as triglycerides. Thanks to this, Vytorin can lower and control your cholesterol levels.

Dosage and Administration

The dose of Vytorin that is prescribed will vary depending on the individual being treated. Follow all your healthcare provider’s directions and read packaging labels carefully to ensure the best results during treatment. Do not change your dose or suddenly stop taking Vytorin without consutling your healthcare provider.

• Swallow tablets whole
• Take with or without food in the evening
• Vytorin should be taken in combination with a cholesterol-lowering treatment program including diet and exercise
• Continue taking Vytorin as prescribed even if you feel well
• Do not suddenly stop treatment
• Store at room temperature away from children and pets

To lower cholesterol and triglyceride levels:

• Most adults start by taking 10mg ezetimibe/10mg simvastatin or 10/20mg once daily
• Those who require a larger cholesterol reduction may start with 10/40mg once a day
• Doses can increase every 2 weeks as needed up to 10/80mg daily
• Adults should not take more than 10/80mg a day

Dosage for coadministration with other drugs:

• When taking verapamil, diltiazem, or dronedarone, your Vytorin dose should not exceed 10/10mg a day
• If you take amiodarone, amlodipine, or ranolazine, your daily Vytorin dose should not exceed 10/20mg
• Adults who take bile acid sequestrants should take their dose of Vytorin at least 2 hours before or 4 or more hours after taking the sequestrant.

Side Effects

Vytorin may cause some side effects while affecting your lipid levels. Talk with your healthcare provider to learn more about any symptoms you may have during treatment.

Common Vytorin side effects:

• Headache
• Muscle pain
• Abnormal liver function test results
• Diarrhea
• Cold symptoms (stuffy nose, sneezing, sore throat)

Serious Side Effects

Some more serious adverse reactions may occur during treatment with Vytorin. Contact your healthcare provider right away if you develop any of the following side effects:

• Unexplained muscle pain or weakness
• Weak muscles in your hips, shoulders, neck, or back
• Difficulty lifting your arms, climbing, or standing
• Fever, unusual tiredness
• Upper stomach pain, decreased appetite
• Dark coloured urine
• jaundice

Allergic Reactions

Do not use Vytorin if you are allergic to ezetimibe, simvastatin, or any of the other tablet ingredients. Stop using this medication and call your healthcare provider if you develop any of the following signs of an allergic reaction:

• Hives
• Difficulty breathing
• Swelling of your face, lips, tongue, or throat

Cautions

• Do not use Vytorin if you have liver problems.
• To ensure your safety during treatment with Vytorin, tell your healthcare provider if you have ever had any of the following:
  • Unexplained muscle weakness or muscle pain
  • Thyroid disorder
  • Liver or kidney disease
  • Liver problems caused by alcohol use
  • If you are older than 65
• Some drugs can interact with Vytorin and cause unwanted reactions. Tell your healthcare provider about all the medications you take, including over the counter medicines, but especially any of the following:
  • Antifungal medicines such as itraconazole, ketoconazole, posaconazole, voriconazole
  • HIV protease inhibitors like indinavir, nelfinavir, or ritonavir
  • Certain hepatitis C protease inhibitors like boceprevir or telaprevir
  • Certain antibiotic medications like erythromycin, clarithromycin, or telithromycin
  • Nefazodone
  • Cobicistat medications
  • Fibric acid medicine to lower cholesterol
  • Cyclosporine
  • Danazol
  • Amiodarone or dronedarone
  • Verapamil, diltiazem, amlodipine, or ranolazine heart medicines
  • Colchicine
  • Lomitapide
  • Daptomycin
  • Large doses of niacin or nicotinic acid
• Avoid ingesting grapefruit products while taking Vytorin because it can cause an increase in adverse reactions.
• Avoid drinking alcohol during treatment with Vytorin because it can increase your risk of developing liver damage.
• Ensure that you follow your entire treatment program prescribed by your healthcare provider including a diet that avoids foods that are high in fat and cholesterol. This helps improve the effectiveness of Vytorin at lowering and managing your hyperlipidemia.
• Do not use Vytorin while pregnant because the medication could cause harm to your baby. Ensure that you use effective birth control to prevent pregnancy during treatment. Tell your healthcare provider immediately if you become pregnant.
• Vytorin may cause your muscle tissues to break down which could lead to kidney failure. Your risk of this condition happening may be higher if you are female, an older patient, of Chinese descent, if you have kidney disease, or if you have uncontrolled hypothyroidism.
• Vytorin is not an approved form of treatment for any child younger than 10.
• Do not administer Vytorin to any girl before she has her first menstrual period.

Form and Strength

This cholesterol and triglyceride lowering medication is available in tablet form.

• Vytorin tablet strengths:
  • 10mg ezetimibe/10mg simvastatin
  • 10/20mg
  • 10/40mg
  • 10/80mg

Each Vytorin tablet strength is available in quantities of 30 and 90.

FAQ

What food should be avoided when taking Vytorin?

During treatment with Vytorin, you should avoid having any grapefruit products because they can increase side effect. You should also avoid drinking alcohol, especially in large quantities, because it can increase your likelihood of developing liver damage. Ensure that you also avoid foods high in fat or cholesterol as prescribed by your healthcare provider to support the effectiveness of this medication.

Should Vytorin be taken with or without food?

Vytorin tablets can be taken with or without food while maintaining the same effectiveness. It is recommended that you take your daily dose in the evening to lower your cholesterol and triglyceride levels and maintain healthy levels throughout the night into the next day. Use this medication exactly as prescribed by your healthcare provider.

Resources:

1. https://www.drugs.com/vytorin.html
2. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=89b860d2-de83-468e-b7e8-76aeec2edca2&type=display
3. https://www.organon.com/product/usa/pi_circulars/v/vytorin/vytorin_ppi.pdf