Safely Buy Prinzide ( Lisinopril/Hctz ) from Canada Prescriptions Plus.

Indications

Prinzide is an anti-hypertensive medication used to treat high blood pressure (hypertension).

This blood pressure medication combines lisinopril, an angiotensin converting enzyme (ACE) inhibitor, with hydrochlorothiazide, a thiazide-type diuretic to lower blood pressure. Lisinopril inhibits the conversion of angiotensin enzymes in the renin-angiotensin-aldosterone system which decreases vasoconstriction to lower BP. Hydrochlorothiazide lowers blood pressure by decreasing peripheral resistance and promoting diuresis.

This anti-hypertensive medication has been found to be more effective at lowering blood pressure than either lisinopril or hydrochlorothiazide therapies on their own. Prinzide is generally well-tolerated and supports cardiovascular health by managing hypertension.

Uses and Dosage

The dose of Prinzide that is prescribed will vary depending on the individual being treated. Follow your doctor’s instructions and read packaging labels carefully to ensure the best results.

• Swallow tablets whole
• Take with or without food
• Most adults take 10 to 80mg of lisinopril with 12.5 to 50mg of hydrochlorothiazide once daily
• If switching from monotherapy, most adults can start taking Prinzide 10/12.5mg or 20/12.5mg
• Adults should not take more than 80mg of lisinopril or 80mg of hydrochlorothiazide
• Tell surgeons you take Prinzide before having any surgeries
• Continue using Prinzide as directed even if you feel well
• Your blood pressure will need to be checked regularly during treatment
• Store at room temperature away from children and pets

Side Effects

Prinzide may cause some side effects to develop while lowering your blood pressure levels. Speak with your doctor for more information concerning any symptoms that you may encounter when taking lisinopril with hydrochlorothiazide.

Common Prinzide side effects:

• Cough
• Headache
• Dizziness
• Tired feeling

Serious Side Effects

Some more serious adverse effects may occur when taking lisinopril and hydrochlorothiazide. If you develop any of the following symptoms, stop using Prinzide and call your doctor right away:

• Light-headed feeling like you might pass out
• Eye pain, vision problems
• Little or no urination
• Weakness, drowsiness, or feeling restless
• Fever, chills, sore throat, mouth sores, trouble swallowing
• Jaundice
• High potassium levels (nausea, tingling, chest pain, irregular heartbeat, loss of movement)
• Low potassium (leg cramps, constipation, irregular heartbeat, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling)
• Low sodium (headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady)

Allergic Reactions

Do not take Prinzide if you are allergic to lisinopril, hydrochlorothiazide, sulfa drugs, or to any other ACE inhibitor. Stop using this medication and contact your doctor if you notice any signs of an allergic reaction.

Prinzide allergy symptoms may include:

• Hives
• Stomach pain
• Difficulty breathing
• Swelling of face, lips, tongue, or throat

You may be more likely to develop an allergic reaction when taking Prinzide if you are African American.

Cautions

Do not use Prinzide if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant.

Do not use Prinzide if you have ever had angioedema or if you are unable to urinate.

Do not take Prinzide within 36 hours of using any medication that contains sacubitril to avoid a drug interaction.

If you have diabetes, do not use lisinopril with any medication that contains aliskiren.

To ensure your safety when taking Prinzide, tell your doctor if you have ever had any of the following:

• Kidney disease or if you are on dialysis
• Cirrhosis or other liver diseases
• Glaucoma
• Heart disease or congestive heart failure
• Asthma or allergies
• Gout
• Lupus
• Allergy to sulfa drugs or penicillin
• If you are on a low-salt diet

Hydrochlorothiazide may increase your risk of developing skin cancer. Avoid exposure to direct sunlight or tanning beds while taking Prinzide.

Avoid drinking alcohol while taking Prinzide because it can lower your blood pressure and cause adverse reactions.

Do not use potassium supplements or salt substitutes while taking Prinzide unless directed to do so with by your doctor to avoid receiving too much potassium and too little sodium.

Move slowly to avoid getting dizzy when standing from a seated or laying position.

Avoid becoming overheated or dehydrated while taking Prinzide.

Consult with your doctor before using Prinzide if you are breastfeeding.

Some other drugs may interact with lisinopril or hydrochlorothiazide and cause adverse reactions. To avoid this, tell your doctor about all the medications that you take, including any over the counter medicines, but especially any of the following:

• Other blood pressure medications
• Lithium
• Everolimus, sirolimus, temsirolimus
• Nonsteroidal anti-inflammatory drugs (aspirin, ibuprofen, and others)

Prinzide is not an approved treatment for anyone under the age of 18.

Form and Strength

This blood pressure medication is available in tablet form.

Prinzide tablet strength:

• 10mg lisinopril / 12.5mg hydrochlorothiazide

The 10/12.5mg Prinzide tablets are available in quantities of 84.

FAQ

What should I avoid while taking lisinopril and hydrochlorothiazide?

You should avoid drinking alcohol while taking Prinzide because it can lower your blood pressure and cause adverse reactions. When taking Prinzide you should also avoid using potassium supplements or salt substitutes because not doing so could lead to high potassium levels and low sodium levels in your system.

Can I take Prinzide at night?

Yes, you can take your single daily dose at night or any other time that is convenient for you. Some studies have shown an increase in benefits when blood pressure medications are taken before bed, however hydrochlorothiazide is a diuretic and may cause you to need to urinate after taking your dose. If Prinzide causes you to urinate more frequently, you can take your dose a few hours before bed.

Resources:

1. https://pubmed.ncbi.nlm.nih.gov/1665176/
2. https://pubmed.ncbi.nlm.nih.gov/29489196/
3. https://pubmed.ncbi.nlm.nih.gov/28613517/
4. https://www.drugs.com/cons/prinzide.html
5. https://www.drugs.com/mtm/hydrochlorothiazide-and-lisinopril.html
6. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=af0c5240-4a98-4b25-b805-d6d3889bdc62