Safely Buy Sintrom ( Nicoumalone ) from Canada Prescriptions Plus.

Indications

Sintrom (acenocoumarol) is an oral anticoagulant medication used to prevent blood clots. It belongs to a class of drugs known as vitamin K antagonists (VKAs).

Acenocoumarol works by partially blocking the reuse of vitamin K in the liver, which is necessary for the production of clotting factors that help the blood to clot and prevent bleeding.

Sintrom is commonly prescribed to reduce the risk of blood clots in conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), atrial fibrillation, and after certain surgeries.

Note that Sintrom requires careful monitoring and dose adjustment to maintain the desired anticoagulant effect, as the optimal dose varies from person to person.

Use and Dosage

The dose of acenocoumarol is individualized by your doctor according to blood clotting time as determined by laboratory tests, called an INR, performed at regular intervals. Keep your lab appointments, as there is a narrow range between too much and too little of the medication. Too much medication may cause you to bleed more. Too little medication may let a harmful clot form.

The usual dose on the first day ranges from 8 mg to 12 mg and on the second day from 4 mg to 8 mg. The usual maintenance dose ranges from 1 mg to 10 mg once daily. Take acenocoumarol at the same time each day.

Different circumstances in your life (e.g., eating certain foods or using certain medications) can cause this medication to work more or less effectively. Ask your doctor or pharmacist for a list of these foods and medications.

Side Effects

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• Diarrhea
• Fever
• Hives
• Itchy skin
• Loss of appetite
• Loss of hair
• Nausea
• Vomiting

Cautions

• Before you begin taking a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breastfeeding, and any other significant facts about your health. These factors may affect how you should take this medication.
• Bleeding: The most serious risk associated with acenocoumarol is bleeding in any tissue or organ. The risk of bleeding is related to the level of intensity and the duration of treatment.
• Kidney problems: If you have kidney problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
• Liver problems: If you have liver problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
• Medical alert: In case of injury or accident, people taking this medication should carry a card or wear other identification (e.g., bracelet or necklace) that states they are taking this medication.
• Medical conditions and other medications: Many medical conditions and medications affect the way acenocoumarol works and affect the dosing of this medication. If you have a medical condition and are taking medications, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
• Always check with your doctor or pharmacist before taking any new prescription or over-the-counter medication, supplement, or herbal product.
• Medical procedures: Before undergoing any medical test or procedure (e.g., minor surgery, tooth extractions, angiography), be sure to tell your healthcare providers that you are taking this medication.
• Stopping the medication: If your doctor has told you that you can stop acenocoumarol, they may recommend that you decrease your dose slowly over time. Do not suddenly stop taking this medication without discussing it with your doctor first.
• Pregnancy: Acenocoumarol should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
• Breast-feeding: Acenocoumarol passes into breast milk. If you are a breastfeeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breastfeeding.
• Children: The safety and effectiveness of taking this medication have not been established for children.
• Seniors: Seniors taking this medication may be more sensitive to side effects and may need closer monitoring by their doctors.

Forms and Strengths

Sintrom is available in the following forms and strengths:

• Sintrom Tablet:
  • 1 mg
  • 4 mg
• Nicoumalone Tablet:
  • 1 mg
  • 2 mg

FAQ

How should I take Sintrom?

Sintrom is usually taken orally once a day, preferably at the same time each day. The dosage is determined based on your individual needs and is adjusted according to regular blood tests to monitor the clotting time (INR).

What should I do if I miss a dose of Sintrom?

If you miss a dose, take it as soon as you remember, unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Are there any dietary restrictions while taking Sintrom?

Sintrom can interact with foods high in vitamin K, which can affect its effectiveness. It is important to maintain a consistent intake of vitamin K-rich foods and avoid making drastic changes to your diet without consulting your healthcare provider.

Can I take other medications while on Sintrom?

Sintrom can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Inform your healthcare provider about all the medications and supplements you are taking to avoid potential interactions.

Can I drink alcohol while taking Sintrom?

Alcohol can increase the risk of bleeding while taking Sintrom. Limit or avoid alcohol consumption.

Resources:

1. https://pubmed.ncbi.nlm.nih.gov/12503504/
2. https://www.medbroadcast.com/drug/getdrug/sintrom