Safely Buy Motegrity ( Prucalopride Succinate ) from Canada Prescriptions Plus.

Indications

Motegrity is a gastrointestinal medication used to treat chronic idiopathic constipation.

Prucalopride is a selective serotonin receptor agonist that stimulates colinic activity and decreases transit time to improve chronic constipation. Motegrity encourages stool movements by causing contractions that ease and increase bowel movements.

This laxative medication offers effective treatment for unexplained chronic constipation and is generally well-tolerated. Because Motegrity doesn’t affect potassium channels or other serotonergic receptors in your blood vessels, the medication has a low incidence of causing cardiovascular issues.

Uses and Dosage

The dose of Motegrity prescribed will vary depending on the individual and the severity of their condition being treated. Follow all your doctor’s instructions and carefully read packaging labels when taking medication.

• Swallow tablets whole
• Take with or without food
• Most adults take 2mg once a day
• Those with renal impairment should take 1mg daily
• Store at room temperature away from moisture and heat

Side Effects

Motegrity may cause some side effects to develop while stimulating bowel movements. Speak with your doctor for more specific information regarding any symptoms you may encounter when taking prucalopride.

Common Motegrity side effects:

• Nausea, vomiting, diarrhea
• Stomach pain, bloating, gas
• Headache
• Dizziness
• tiredness

Serious Side Effects

Some more serious adverse effects may occur when taking prucalopride. Stop using Motegrity and call your doctor if you develop any of the following symptoms:

• Unusual changes in mood or behaviour
• Ongoing or worsening depression
• Suicidal thoughts or actions
• Feeling sad or hopeless

Allergic Reactions

Do not take Motegrity if you are allergic to prucalopride or any of the ingredients in the tablets. If you notice signs of an allergic reaction, stop using this medication and contact your doctor.

Motegrity allergy symptoms may include:

• Hives
• Difficulty breathing
• Swelling of face, lips, tongue, or throat

Cautions

Do not take Motegrity if your intestines are blocked or if you have any of the following:

• Severe constipation
• Inflammatory bowel disease (Crohn’s disease, ulcerative colitis, or others)
• Toxic megacolon
• Intestinal perforation

To ensure your safety in taking Motegrity, tell your doctor if you have ever had any of the following:

• Kidney disease
• Depression
• Mood disorder
• Suicidal thoughts

Consult with your doctor if you are pregnant or breastfeeding before using this medication to ensure the safety of you and your baby.

Prucalopride is not an approved treatment for anyone younger than the age of 18.

Some other drugs may interact with Motegrity and cause adverse effects. Tell your doctor about all the medications you take, including over the counter medicine, vitamins, and herbal products to ensure your safety.

Form and Strength

This constipation medication is available in the form of film coated tablets.

Motegrity tablet strengths:

• 1mg
• 2mg

Both the 1 and 2 mg Motegrity tablets are available in quantities of 28 and 84 while the 2mg ones are also available in groupings of 100.

FAQ

What type of drug is Motegrity?

Motegrity uses prucalopride, a selective serotonin receptor agonist, to stimulate bowel movements. The drug does this thanks to its colonic prokinetic activity which helps improve stool transit time and make it easier to complete bowel movements.

How should I take Motegrity?

Motegrity can be taken at any time of the day, with or without food. Your single dose may be easiest taken at the same time each day to build a routine and make it easier not to forget your doses. Follow all instructions provided by your doctor, such as dosing schedules and amounts.

Resources:

1. https://pubmed.ncbi.nlm.nih.gov/33968518/
2. https://pubmed.ncbi.nlm.nih.gov/31096799/
3. https://www.drugs.com/motegrity.html
4. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bca1e4c6-4b2b-4876-8ab3-654629c4ff1b
5. https://www.motegrity.com/what-to-expect/frequently-asked-questions